Studies on the synthesis of peptides containing dehydrovaline and dehydroisoleucine based on copper-mediated enamide formation

• Franziska Gille and
• Andreas Kirschning

Beilstein J. Org. Chem. 2016, 12, 564–570, doi:10.3762/bjoc.12.55

• ornithine as well as for the tripeptide 44 containing dehydroisoleucine with the correct stereochemistry. Keywords: catalysis; dehydroamino acids; Hartwig–Buchwald reaction; myxovalargin; peptides; Introduction Dehydroamino acids [1] are rare amino acids that are constituents of many oligopeptides from